
June 2026 (Vol. 8 Issue 1)
The Pitfalls of Next-Generation Sequencing: Revisiting the Importance of Clinical Actionable Results in Targeted Genomic Testing and Precision Oncology
Amanda Haryono
30/06/2026
With Next-Generation Sequencing having transformed genomic testing, its increased implementation has exposed major limitations, including signal degradation, variant miscallings in low-frequency signals, and errors in reading regions with Copy Number Variations (CNVs). As a result of this, data collected by such ...
Thematic Analysis of Criminal Justice Professionals on Criminal Behavior
Key Burr
30/06/2026
Within this qualitative thematic analysis of professionals in the field of criminal justice, there is an emphasis on how multiple perspectives are an important factor to consider when understanding what aspects contribute to criminal behavior. It explores continuous misinterpretations of crime within the ...
Language and Empathy: How Bilingual Schools Shape Immigration Views
Anabelle Ritchey
30/06/2026
This study examined how bilingual schools influence their middle school students’ perspectives on Spanish-speaking immigrants, addressing a gap in existing research at the intersection of bilingual education, empathy, and immigration attitudes. ...
Determinants of Social Media View Growth: Evidence from Channel-Level and Post-Level Analysis
Andrew Yum
30/06/2026
This study examines the drivers of social media performance across both large and moderate following accounts. We combine channel-level panel regressions with post-level predictive benchmarking, drawing on top-account snapshots from TikTok and YouTube collected in June, September, and December, ...
Automatic Arterial Wall-Finding Algorithm
Samir Dewan
30/06/2026
Cardiovascular disease remains one of the leading causes of mortality worldwide, creating a growing need for accurate, efficient, and reliable vascular monitoring techniques. Arterial wall detection plays a critical role in assessing vascular health by enabling measurements such as arterial diameter, wall ...
The Shadow of the Past: Distinguishing Soviet Legacy from Global Trends in Post-Soviet Youth Nihilism
Alisher Yunusov
30/06/2026
The dissolution of the Soviet Union in 1991 was expected to result in a psychological break from communist values. Thirty years later, especially within youth in Central Asia, that anticipated psychological break is nowhere in sight. This paper argues that post-Soviet youth nihilism is a distinct ...
The Impact of COVID-19 on U.S. Internal Migration
Ho Yin Pak
30/06/2026
Internal migration refers to the movement of people within a country; internal migration patterns vary by differing demographic groups, socioeconomic factors, and temporal factors. Internal migration is an important mechanism for individuals to improve their socio-economic status and find new employment ...
Evaluating the Trade-offs of CAR-T cell Therapy through the correlation of Societal perceptions, Split dosages, and B-cell aplasia
Yi-Tzu Lin
30/06/2026
This study evaluates the trade-offs of Chimeric Antigen Receptor (CAR) T-cell therapy by correlating B-cell aplasia under split dosage regimens with the societal perceptions of Taiwanese parents. While CAR-T cell therapy offers significant oncological benefits, its severe toxicities pose substantial physical ...
Assessing the Importance of Eye Position, Pupil Position, and Point of Regard as Relevant Biomarkers for Autism Spectrum Disorder Detection Using Deep Neural Networks (DNNs) and Long Short-Term Memory (LSTM) Models
Shriya Pawgi
30/06/2026
More efficient and precise diagnoses, enabled by identifying important biomarkers, can significantly improve the standard of living of those with ASD, or Autism Spectrum Disorder. This study investigates the comparative performance of Deep Neural Networks (DNNs) and Long Short-Term Memory (LSTM) ...
The Evolving Landscape of HPV-related Cervical Malignancies: a Comprehensive Review
Analucia Ramos Cornejo
30/06/2026
Cervical cancer is the fourth most frequently diagnosed and fourth most deadly cancer in women globally, despite it being largely preventable due to its strong association with human papillomavirus (HPV) infection. While widespread implementation of HPV vaccination and cervical screening has led to marked ...
Perceptions of AI and Patterns of Use among Attorneys in Richmond, Virginia
Aaiza Rassiwala
30/06/2026
This study examines how attorneys in Richmond, Virginia, perceive and use artificial intelligence (AI) within legal practice. As AI tools become further integrated in legal workflows, questions have emerged about accountability, transparency, bias, and professional responsibility in regards to AI. ...
Does Economic Growth Exhibit a Systematic Relationship With Wildlife Trade?
Neil Mehra
30/06/2026
Illegal wildlife trade (IWT) is regarded as a major environmental issue. Economic growth is thought to increase wildlife trade by expanding markets and increasing purchasing power. However, empirical analyses linking macroeconomic change to IWT remain limited. This paper examines whether economic ...
Future Directions in Mucosal Vaccines: Adjuvants, Routes of Administration, and their Role in Immune protection
Yosha Bhardwaj
30/06/2026
This literature review explores the use of mucosal vaccines as a strategy to enhance communal immunity and prevent infectious diseases. It examines both the medical and socioeconomic impacts of mucosal vaccines, highlighting their role in improving public health outcomes. ...
Students for Fair Admissions v. Harvard: A Consequential Supreme Court Ruling Sparking Considerable Debate and Clarifying Decades of Affirmative Action Jurisprudence
George Papazoglu
30/06/2026
The United States Supreme Court has historically viewed the practice of affirmative action, where racial minorities are given a boost in areas such as university admissions, with heightened scrutiny. This paper examines the Supreme Court’s decision in Students for Fair Admissions v. The President and Fellows of ...
Molecular Mechanisms and Epigenetic Regulation in Estrogen Receptor-Positive Breast Cancer: Implications for Therapy and Resistance
Devangi Bhargava
30/06/2026
Estrogen receptor-positive (ER+) breast cancer represents the majority of breast cancer cases and is characterized by complex molecular heterogeneity shaped by genetic and epigenetic factors. Epigenetic regulation—including DNA methylation, histone modifications, and non-coding RNAs—plays a pivotal ...
Does Investor Sentiment Predict Market Volatility? A Regime-Based Analysis Using Social Media Data
Arsh Sinha
30/06/2026
This paper examines the relationship between investor sentiment and stock market volatility using a regime-based empirical framework. The analysis draws on 367,665 tweets referencing 101 major global stocks over the period January 2017 to December 2018. Sentiment volatility is constructed as the mean ...
Genomic Safe Harbours and Human Gene Therapy: A Review of Candidate Sites, Evaluation Criteria, and Functional Applications.
Nandini Pangal
30/06/2026
Genetic engineering, particularly insertion therapies like CRISPR-Cas9, depends on the stability and predictability of transgene integration, modification, or deletion into human DNA. Unintended outcomes can occur due to random or inadequate targeting, ranging from increased oncogene expression to ...
A Cultural Metamorphosis: How Japanese Musicians Transformed Jazz into City Pop
Edward Rim
30/06/2026
City Pop, a genre that emerged in Japan in the late 1970s and flourished through the 1980s, demonstrates that new styles of music rarely emerge in isolation. Shaped by post-war Japan's economic boom, urbanization, and the influx of Western cultures, City Pop is an amalgamation of jazz and Japanese ...
The Rhythm of Grief: Metrical Disruption as Embodied Poetics in Latin Elegy
Nathaniel Im
30/06/2026
This review synthesizes scholarship across four fields—classical philology, ancient rhetorical theory, Roman funerary epigraphy, and modern biomechanical research on emotion and movement—to examine a question approached piecemeal rather than as a coherent debate: whether the prosody of Latin elegy ...
Molecular Recovery: Tracking Muscle Gene Expression After Exercise Stress
Gulmehr Contractor
30/06/2026
In order to truly understand when the body has completely healed at the cellular level after intense exercise, this paper goes over the molecular mechanism of muscle recovery, and what it means to feel “rested.” This study analyzes transcriptomic data from the NCBI Gene Expression Omnibus (GEO) ...
Yellow Envelope Act: A Causal-Comparative Analysis on the Effects of Subcontracting Regulatory Policies
Noah Jung
22/06/2026
To investigate the potential effects of the Yellow Envelope Act on the job security of young construction workers in South Korea, a causal-comparative analysis of unemployment-risk trends surrounding the implementation of similar subcontracting regulations was conducted using OECD Data Explorer data ...
Silent Struggles: Harassment and Gendered Safety Challenges of South Asian Youth in Hong Kong
Tara Ramachandran
20/06/2026
This paper investigates safety concerns, harassment, and gender bias among South Asian teenagers in Hong Kong. While they are a fast-growing ethnic minority, comprising 1.4% of the population, they face disproportionate discrimination. Hong Kong is well known as a multicultural hub, yet statistics reveal that ...
Analysis of Wingtip Devices Using CFD Simulations and A CVAE Model
Ruohan Wang
19/06/2026
The wingtip of an airfoil is considered a critical aerodynamic interface. While the size of a wingtip is small relative to the wing, the importance of its effect on fuel consumption, weight control and aerodynamic behavior during turbulence is significant. This study investigates the design of wingtip ...
AI and Wage Inequality in the United States, 2010-2024: Why Theory and Data Diverge
Sreesh Manayakar
19/06/2026
This paper investigates the impact of artificial intelligence on wage inequality and labor market equilibria within the United States between the years 2010 and 2024. Task-based economic models predict that artificial intelligence should displace routine middle-skill jobs while enhancing the efficiency of high-skill ...
“Not Unwell Enough”: The gap between Mental Health Discourse and Treatment Seeking Among Post-Pandemic Adolescents
Ramey Manchanda
19/06/2026
The COVID-19 pandemic disrupted adolescent mental health and development in unprecedented ways, yet few studies have examined how young people retrospectively interpret their experience and construct thresholds for help-seeking.This qualitative study explores how adolescents who came of age during the ...
Votes Without Voices: Democratic Erosion and Legal Exclusion in Benin, 2016–2026
Kristen Gately
19/06/2026
This article examines the mechanisms through which Benin—once widely regarded as a democratic model in sub-Saharan Africa—underwent systematic democratic erosion between 2016 and 2026 under President Patrice Talon. Drawing on Freedom House indices, electoral commission records, regional court ...
Diagnosis of infertile horse and cattle via cytogenetic and molecular analyses
Eun-Sang Choi
19/06/2026
In this study, we present one case each of a horse and a cattle that underwent chromosomal analysis due to infertility and/or subfertility. We performed PCR (polymerase chain reaction) analysis in conjunction with karyotyping and FISH (fluorescence in situ hybridization) to diagnose potential chromosomal ...
Estrogen mediated differential regulation of APOE4 and its Role in Neurofibrillary tangle formation and Alzheimer’s Disease progression
Alexia Fernandez
19/06/2026
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder affecting around 50 million people worldwide, with cases expected to triple by 2050. Women exhibit almost twice the risk of developing AD compared to men, which could be explained by estrogen-mediated differential regulation of APOE4 ...
Science Before System: The Hidden Physical Foundation Beneath Engineering and Artificial Intelligence
Landry Silvers
19/06/2026
Physics is not just a discipline. It is the language foundational to everything engineers build and every system AI attempts to encapsulate. This paper argues that students pursuing STEM careers benefit greatly from grounding themselves in physics before specializing in engineering or artificial intelligence ...
Use of Video Games in High School Curriculum to Mitigate Mental Health in Adolescents
Sahasra Kalva
19/06/2026
Adolescent mental health has declined in recent years, with nearly 40 percent of high school students in 2023 reporting persistent sadness or hopelessness. Traditional school-based interventions such as mindfulness programs, digital therapy apps, and depression screenings have produced inconsistent results ...